LDH

Allgemeines

Diagnostic significance has been ascribed to elevations of CSF LDH activities in cases of cerebrovascular diseases, bacterial menigitis, head injury, primary brain tumors, and CSF metastases from solid or hematological malignancies, such like central nervous system (CNS) leukaemia. Increases in CSF LD levels also occurred in patients with other neurological disorders, such as hydrocephalus, raised intracranial pressure, and epileptic seizures. The LDH isoenzyme pattern, especially in children CSF, may be of clinical diagnostic value in bacterial or non-bacterial meningitis, particularly when culture results are pending.

Bewertung

High levels of lactate dehydrogenase in cerebrospinal fluid are often associated with bacterial meningitis. In the case of viral meningitis, high LDH, in general, indicates the presence of encephalitis and poor prognosis.

Schlüsselworte

Lactate